Magnesium-L-threonate and Brain Function 2012 Update

by rob britt on January 14, 2012

Magnesium-L-Threonate and Brain function, which I originally wrote two years ago has been a very popular post garnering many comments and questions, so I felt justified in giving this update for those interested.

Two years ago it was undergoing testing in humans to help with brain function and it was felt that taking magnesium supplements alone would not give the added benefits that the L-Threonate would render. L-Threonate is added to aid in bioavailability, which means the magnesium actually gets into your bloodstream and is usable by your body. In 2010, when I wrote my earlier article,  you could only get the powder and not get the supplement in capsule form. That has changed and there are now a number of places to get the supplement.

One that has come up from a number of readers is Sabre Sciences. They have what they call iMagT.  Cerebral Health also sells a version of Magnesium L threonate. A third source is Swenson Vitamins. I am not vouching for these manufacturers, just passing on the information. I am looking into another company right now called Life Extensions, which seems to be pretty legit. More on that as I learn about them. And here’s a link from Amazon.. Neuro-Mag™ Magnesium L-Threonate, 90 vegetarian capsules

But for people who want to stay sharp (as I mentioned in the original article)  there is also the definite “use it or lose it” school of thought. I am totally in this group as well. My mom is 83 now and still very sharp. She does daily crosswords, word search and is a voracious reader. She recently bought  a netbook and is now surfing the web and learning more all the time. Her long and short term memory seems to be as sharp as ever to me. Way to go Mom!

One cool thing about the internet is that you never know what you are going to stumble across. It might be something as mind numbing as Awkward Family Photos (don’t go there if you don’t want to laugh and get distracted) but it can also provide something as cool as Lumosity, which is a brain training website I’ve become somewhat addicted to. Addicted in a good way. The games there (some are free and some cost a couple bucks) are fun and are specific to exercising your brain.

{ 11 comments… read them below or add one }

LILA January 22, 2012 at 6:18 pm



rob britt
January 23, 2012 at 6:56 am

Hello Lila, I don’t know that MagLThreonate will do a lot for your foot and leg area. It has mostly been tested for helping with neurological function (brain and nervous system) I would recommend taking Phosphotidyl Choline. PC helps all your other supplements work better, plus supports heart and liver health. It is also sometimes sold under the name lecithin.

I do recommend taking Magnestium LThreonate though. It has been tested to help with brain function as we age, fighting Parkinsons and Lou Gehrig’s Disease. My mom is 83 and I recommended both of these to her. A quick disclaimer: I am not a doctor and you should ALWAYS talk to your doctor about adding supplements to your regimen. Especially when you are on a few prescriptions…

Cheryl March 14, 2012 at 8:47 am

Can you tell me if Magnesium L-Threonate would be safe for someone with ESRF who is on dialysis? And is there any anecdotal evidence to suggest it might be helpful for the effects of so-called “dialysis dementia”?



rob britt
March 15, 2012 at 4:58 am

Hi Cheryl, I am not a doctor so I can’t really answer your question. the L-Threonate is (to my understanding) more a carrier to enhance magnesium into your blood stream to make it bio-available, so if you are okay to take magnesium, I would imagine that this would have no other impacts than that supplement. again, I am not a doctor so that is personal opinion only, not advice. I also don’t have any anecdotal evidence on the dialysis dementia. If it is connected with neural activity/brain function I would think it would have a positive impact. I am taking this supplement, so my own personal experience will be detailed after I have given this some time to have impact. Thanks for the comment.

Bob Greene March 16, 2012 at 10:58 pm

Rob– Here is additional information on two points you raised–

Your article states, “… A third source is Swenson Vitamins. I am not vouching for these manufacturers, just passing on the information. I am looking into another company right now called Life Extensions, which seems to be pretty legit…”

1. “Swenson Vitamins” is, in fact, Swanson Vitamins, and your readers can find Swanson at The company is based in North Dakota, which suggests they must be very good at what they do to draw the nation to their thriving little business. My mother began ordering from them because Swanson keeps prices low and charges only $4.99 for the entire shipment. Eventually, I followed Mom’s advice and counsel and placed a few orders with Swanson, myself, and am very pleased with both Swanson products and its customer service.

2. Life Extension Foundation is a non-profit educational foundation ( whose toll-free number 800-444-4440 provides a health adviser (in some cases, an M.D. or N.D.) who can discuss in general terms how vitamins can improve overall health. LEF advisers are careful to emphasize phone contacts and exchange of information do not constitute a medical or therapeutic relationship, but I have found their information of highest quality and without a trace of marketing agenda. In fact, so valuable and up-to-date has been their information, the magazine, alone, is worth the cost of membership.

Membership for LEF is $75 for an entire year, providing a 12-issue subscription to Life Extension Magazine, and a discount on LEF products. Shipping is a flat $5.50 for ground shipment.

First year membership also comes with a large reference book on effective protocols for resisting disease. The book is under revision, with the possibility of both CD/DVD as well as printed paper formats. On the second year of membership (renewal), LEF provides a $95 credit to apply to LEF products of interest. LEF memberships are an attractive gift for friends and family members.

rob britt
March 17, 2012 at 9:02 am

Thanks for the information Bob. Really good stuff and great to know! appreciate it!

carol vicini
March 29, 2012 at 7:57 pm

I began using LEF mag. l threonate dec. 2011. After three weeks, my mood changed significantly. I had been having bad dreams with falling out of bed . I noticed that I had no more bad dreams and haven’t fallen out of bed until last week, when I neglected to take my mag. l threonate for one day. I am sporting a bruised nose, having dived out of bed, acting out a scary dream. I will not forget to take my mag. again.

Jane April 9, 2012 at 8:12 pm

I just bought a Product called Mind -Max made by Nature’s Sunshine Products…. I just found out about it from a Holistic Center I go to …. I have taken one dose I have to say I can feel a difference….. maybe it is a Placebo effect but I really don’t think so . Anyways I think it is worth trying if it enhances a person well-being…… of course I am not a doctor… just trying to stay happy and healthy….

Bethany April 29, 2012 at 9:00 pm

@carol vicini

You might want to look into REM behavior sleep disorder. I’m glad the Mag helps.

Glen February 17, 2013 at 11:51 pm

Hi, I was hoping I could ask you for an update on your experience with magnesium threonate? I am esp interested in any cognitive effects you noticed and how long it took for you to begin seeing these or any other consistent effects. Thanks so much,


rob britt
February 18, 2013 at 6:37 am

Thanks for asking Glen. It’s a bit hard to say what impact the mag threo has had without a control, but I would say that I have in the past had some “nervous hand” symptoms. They seem to have gone away for the most part. Part of the reason for taking this in the first place was those tremors, plus seeing a more advanced tremors in one of my older siblings. (I am fifty, she is sixty) I also do think my memory retention is better since I’ve been taking them. I’ve been fairly consistent with taking this supplement for a few years now and it’s one that I believe makes a real discernible difference. Of course all supplements can have a bit of placebo effect. The impact of this wasn’t immediate. It took about thirty days before I really started noticing a slight change. That being said I still do recommend this.

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