Magnesium-L-threonate and Brain Function

by rob britt on February 2, 2010

I have been concentrating a lot on supplements lately and diet, but there is more to life than those aspects (although diet and supplements are very important.)

Increase Brain Function

Increase Brain Function

I was reading an interesting article on magnesium. More and more research is showing that most diets are not including enough magnesium to help with deteriorating brain function. Of more interest to some folks (especially older folks) is that you can actually increase the functionality of your brain with increased brain function.

A study done at MIT and Tsinghua University in Beijing was done to test the impact of magnesium on the learning abilities, working memory and short and long term memory in lab rats.  The study showed that people who got less than 400 mg of magnesium per day were more at risk for various diseases. Magnesium is generally found in green leafy veggies, yet another reason to eat them in mass quantities. But as people age they tend to get less and less of this mineral which has shown to help with memory and other brain functions. A fact I was unaware of is that half the population in industrialized nations don’t get enough magnesium. Who knew? Check your multi-mineral to make sure you are getting enough… Link to original article….

But for people who want to stay sharp into old age there is also the definite “use it or lose it” school of thought. I am totally in this group as well. My mom is 82 and still very sharp. She does daily crosswords, word search and is a voracious reader. Now the books she reads are sappy romance novels for the most part, but at least she’s using her brain. Her long and short term memory seems to be as sharp as ever to me. Way to go Mom! She even is using e-mail, which is something many folks over 60 are missing out on. Don’t know how I’d get by without the internet and I hope I never have to find out. Neuro-Mag™ Magnesium L-Threonate, 90 vegetarian capsules

One cool thing about the internet is that you never know what you are going to stumble across. It might be something as mind numbing as Awkward Family Photos (don’t go there if you don’t want to laugh and get distracted) but it can also provide something as cool as Lumosity, which is a brain training website I’ve become somewhat addicted to. Addicted in a good way. The games there (some are free and some cost a couple bucks) are fun and are specific to exercising your brain.

{ 35 comments… read them below or add one }

betty spooner February 5, 2010 at 4:22 pm

would like to know where to purchase the new magnesium L-threonate? thank you.

rob
Twitter:
February 5, 2010 at 5:43 pm

the trials have just recently been completed, and as far as I know, no one has brought the product to market yet. L-threonate has been added to calcium for the same purpose as adding it to the magnesium – better bio-availability. Possibly you could take one of those calcium L-threonate products along with your magnessium supplement to get added benefit, but that it just speculation on my part. When I find a source for the magnesium l-threonate, I will post it here.
Thanks for the question.

marsha February 18, 2010 at 1:01 pm

I am also trying to find where I can purchase…….if anyone knows please, please post!!..thank you

Percy Mayeaux April 13, 2010 at 8:44 am

76 yr old man well experienced in nutrition and supplements wants to find source to purchase magnesium-L-theronate [MgT]
Someone out there ? ! ?…..let me hear from you . Thanks,
Percy

Cy June 3, 2010 at 8:21 am

Still no source. I am wondering why someone isn’t looking at this from a business perspective and marketing this stuff. This could have an amazing impact on medicine. With dementia and Alzheimer’s running in my family, I would love to be able to get this to them.

I mean how hard is it to find a chemist and get a pill press?

Martha Giffen June 3, 2010 at 2:01 pm

Being a babyboomer and watching my own parents age, I am a firm believer in keeping your brain active. I have seen it work firsthand! However, I have also seen the devastating effects of dementia. This one drug could save a whole generation from going through what we have watched our parents go through! Thanks for the info :)

Rob July 25, 2010 at 8:29 am

Resource for “MagnesiumL Threonate” is Sabre Sciences, they have a product called “iMagT” that the formulate. If anyone is looking for this product contact them at http://www.sabresciences.com/ I did notice that their website does not list the product, but it is available.

Julie August 6, 2010 at 6:13 pm

Yes, I have tried the “iMagT” from Sabre Sciences and it is a great product. It is a powder form that you have to mix into water and take twice a day. It really works!

Pradeep August 16, 2010 at 8:56 pm

sabresciences.com has it…

Orchard Chemicals Ltd. in China will ship to you door but you have to buy a min of 1 kilo

Pradeep August 16, 2010 at 8:57 pm

sorry about this – with sabresciences you have to contact them – it’s not on thier website…

Julie January 12, 2011 at 6:02 pm

Magnesium L-Threonate is available through Sabre Sciences, a research lab in California. You need to call or email them as it is not advertised on their website. It is about $40 and is in a powder form that you blend into water or juice.

tonyj February 1, 2011 at 2:39 am

Taking L-threonate may have an additional benefit. The following study was done in Korea. And yes, the study was done in vitro.

Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosterone- induced dickkopf-1 expression in human hair dermal papilla cells

In a previous study, we recently claimed that dihydrotestoster-
one (DHT)-inducible dickkopf-1 (DKK-1) expression is one of
the key factors involved in androgen-potentiated balding. We
also demonstrated that L-ascorbic acid 2-phosphate (Asc 2-P)
represses DHT-induced DKK-1 expression in cultured dermal
papilla cells (DPCs). Here, we investigated whether or not
L-threonate could attenuate DHT-induced DKK-1 expression.
We observed via RT-PCR analysis and enzyme-linked im-
munosorbent assay that DHT-induced DKK-1 expression was
attenuated in the presence of L-threonate. We also found that
DHT-induced activation of DKK-1 promoter activity was sig-
nificantly repressed by L-threonate. Moreover, a co-culture sys-
tem featuring outer root sheath (ORS) keratinocytes and DPCs
showed that DHT inhibited the growth of ORS cells, which
was then significantly reversed by L-threonate. Collectively,
these results indicate that L-threonate inhibited DKK-1 ex-
pression in DPCs and therefore is a good treatment for the pre-
vention of androgen-driven balding. [BMB reports 2010; 43
(10): 688-692]

tonyj February 1, 2011 at 9:04 pm

As Julie said, Sabre Science sells the Magnesium L-Threonate as part of their two products. You’ll have to contact them for the price. I just don’t know what the correct amount would be for daily intake.
info@sabresciences.com

iMagT (Mood, memory, concentration)
Per tsp: 200mg Magnesium L-Threonate, 2500mg inositol

iMagT Plus (sleep, metabolism, muscle mass, immune function)
Per tsp: 500mg Inositol, 200mg Magnesium L-Threonate, 600mg L-Ornithine, 500mg L-Arginine, 500 L-Lysine, 500mg L-Glutamine, 10mg Zinc

MLT500 April 25, 2011 at 9:25 pm

If people are still interested, my partner and I are working to bring Magnesium l-threonate to the US. For more details, see http://www.mlt500.com.

It’s a big investment so we’re gathering names for an interest list – the more people who sign up, the sooner we will be able to launch, so if you are interested please let your friends know.

Erin June 2, 2011 at 12:25 am

I have been on an adrenal protocol with Dr. Borkin at Sabre Sciences for a little over a year with fantastic results. After the first phase of decreasing my cortisol and increasing my testosterone level via transdermal cremes infused with amino acids and Vit B12 several key precursors, he recommended I add the ImagT formula that he has formulated there at their lab. It is amazing stuff. What I’m not sure about is if they will just sell it to someone on demand or if you have to be engaged in a protocol of some kind and working with them directly. If so, another way to procure it would be to have your healthcare provider either mainstream or alternative be the one to interface with the lab to procure the Magnesium L-Threonate w/ inositol blend called I Mag T. Hopefully it will be readily available to all. Just to pass on other really cool products that they have developed are: a detox soap, a transdermal creme for shingles and cold sores full of amino acids that cuts down the active time of the blisters, and my favorite is their Ultra D detox capsules that take about a month. It has truly changed my life and my hormones are correcting themselves because of the incredible detailed protocol I did with them. I am not needing any bio-identicals or any other major things now. My liver is making everything it needs and my neurotransmitters are in better balance as well. So….yes, call Sabre Sciences today and feel better sooner!!!

rob britt
Twitter:
June 2, 2011 at 8:12 am

Thanks for the comment Erin. Glad to hear that the I Mag T helped you out. It’s always helpful to have personal accounts of impact.

Jason July 14, 2011 at 6:16 am

Hello, I wanted to let you know I found source for bulk Magnesium L-Threonate . You can find it at http://www.cerebralhealth.com (I just happened to see it while I was purchasing other products). Hope this is helpful!

Jason July 14, 2011 at 6:29 am

Rob,

I wanted to know if you heard about nootropics for brain function? I only pass this on because so many people are on medications for ADHD/ADD or for anxiety that I believe have harmful side effects. Additionally, there is a huge amount that purchase sugar/caffeine loaded drinks to give them a boost. Well I can tell you I have found an amazing alternative and solution for increasing focus/memory/anti-anxiety through a remarkable substance called piracetam (taken with choline citrate). After experimenting with it I then found other supplements that are equally as profound with practically no side effects or crashes or sleep disturbances. So in addition to piracetam, check out Alpha-GPC, Sulbutiamine & Centrophenoxine. I am trying to tell as many people as I know because the benefits have been life changing. I just hope even ONE person reads this comment and learns that there ARE alternatives to harmful stimulants and sedatives.

Thanks,

Jason

rob britt
Twitter:
July 14, 2011 at 6:46 am

Jason, Thank you so much for the additional source and for the first hand information. I love reading about various studies on supplements (for the skeptic in me, I need those) but personal accounts are also very heart warming. I hope that many people read your comment on Magnesium L-Threonate, and look into the piracetam, Alpha-GPC, Sulbutiamine and Centrophenoxine. I know I will be checking them out.
rob britt recently posted..Internet Search Engines? All searches are not created equal

Noelle Drew September 22, 2011 at 5:01 pm

well I contact sabre laboratories in carlsbad (you can find a long list in susanne sommers book “index” of labs) and I took a saliva test, they send you the tubes etc, cost with also urine test..was 300+ and Ive been doing this since 2009 every year is good…and Iam now 61, and my levels had gone down sugnificantly…well one of the powders i take is L-Theonate,and magnesium..they may put something else in the powder…cost about 39.00 I believe, plus a couple of hormone creams, I had very low serotonin…one for the am one for the pm….after sleepling 5-6 hours a night, am sleeping 8-9 hours…but also found, I should not be eating Carbs, and no wheat…take guercetin and a probiotic…and also a same-E,but they make theres at their labs…seems like its better than over the counter…Iam dropping weight, now that not eating wheat and carbs…amazing…I believe one should take responsibility for ones health etc…what with healthcare, and nobody cares about you like you do…right? good luck. any little change helps..also..take miineral drops..couple of them added to H2O or soups what ever…you can get that at health food store…about 30.00, have a smaller one for 15.00….tootles

John September 26, 2011 at 1:43 pm

Swanson’s lists magnesium l-threonate on page 5 of the newest catalog.

Helen September 26, 2011 at 8:55 pm

Yes i see someone has already posted where you can buy magnesium l-threonate . Swanson has just started selling it i am going to try it. Their phone number is 1-800-437-4148 website is http://www.swansonvitamins.com good luck helen

Marc Latrique October 25, 2011 at 8:26 pm

I found and ordered from China 1 Kilograms of Magnesium L-Threonate for the incredible price of $150 including shipping.
Mention them that you were referred by Mr. Marc Latrique please:
Contact Nancy there:
Nancy Liew

Shanghai Soyoung Biotech. Inc.
Email: sales6@sybio.com.cn
Cell: 018606291421
Tel: 86 21 20230163/60484973
Add: 40-601,Lane 688, Fanjin Road,
Pudong, Shanghai 201208 P.R. China
Please spread the word through your Forum or any other mean.
My time is kind of short right now.
Marc Latrique
ML3115@aol.com
718-779-4013

Mason Bagwell November 2, 2011 at 10:25 am

YOU CAN BUY IT AT swansonvitamins.com

Steven Williams November 10, 2011 at 12:27 pm

Neuro-Mag Magnesium L-Threonate, 90 vegetarian capsules
http://www.lef.org/newshop/items/item01603.html

Life Extension comes to the rescue again

Kim November 30, 2011 at 2:59 pm

Lots of good info from the makers of Magtein, the proprietary Mg L-threonate product here: http://magtein.com/index.html

I have a severe Mg deficiency (even with supplementation) and have tried almost all kinds of oral Mg products over the years. Mg Malate has been my Mg-of-choice for some time now and it has helped reduce the frequency of angina attacks and reduces the amount of muscle twitching that I have. But it has done nothing for my cognitive problems.

I’m a good test case. I just ordered a month’s supply from Swanson and will report back at the end of the month.

rob britt
Twitter:
November 30, 2011 at 4:22 pm

Thanks Kim. Looking forward to hearing back from you. If you want to do a guest post on the blog about your thoughts/experience on this, let me know.

Susan T. December 9, 2011 at 3:03 pm

Go to Life Extension website . They seel it. http://www.lef.org.

Susan T. December 9, 2011 at 3:06 pm

Life Extensions sells magnesium threonate. Just go to their website http://www.lef.org.

cgl December 12, 2011 at 8:19 pm

Magnesium L Threonate can be purchased through Life Extensions vitamins. Check it out online.

Helen January 2, 2012 at 2:31 pm

Magnesium L-Threonate can be purchased from SWANSON VITAMINS online I intend to try it myself the price is listed in the catalog as $29.99 and yes the reports say most of us are short on magnesium but it is very difficult to know through tests

Dee January 2, 2012 at 11:25 pm

Magnesium-l-threonate is available from Life Extensions… called Neuro-Mag (runs about $29 for 90 capsules). Can be found on Life Extension or Amazon. Thinking of taking it to see if it helps with memory. I am in my 30′s but interested in memory improvement. Let me know if any of you try it and see results. I’d like to know before I buy it.

Bob January 12, 2012 at 6:26 pm

No one reads the comments, . they probably didn’t take their Magnesium L Threonate. In case you missed it, life extension, swanson vitamins, and sabre sciences carry it.

vasiliki January 16, 2012 at 9:02 pm

You can purchase Life Extension Magnesium L-Threonate on amazon.com. Shipping is free @ 28.95 for 90 tablets.
Neuro-Mag™ Magnesium L-Threonate, 90 vegetarian capsules

Tamlal April 16, 2012 at 1:06 am

Nature’s Sunshine, “Mind-Max” is available in the States as a new product that has just been released. I have had anaphylactic reactions to OTC supplements in the past so I had to really research my vits/minerals. I became a distributor to help myself and my friends based on their amazing products…and NO reactions to anything I’ve tried. I’m looking forward to some increased brain power and a good night’s sleep for exams tomorrow. *fingers crossed*. (I’m pretty sure you can just buy off of their website, but if you can find a distributor that’s not after making money, you can get a better price.

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